Since RBCs oxygenate the body, when a person is anaemic, their heart has to work harder to pump the quantity of blood needed to get adequate oxygen around their body. Anaemia isn’t a disease in itself, but a result of a malfunction somewhere in the body. This blood condition is common, particularly in females as they lose blood during their menstrual cycle every month.
Red blood cells explained
Blood cells are produced in the bone marrow. Each red blood cell contains a protein called haemoglobin. This protein gives red blood cells their characteristic red colour. Oxygen molecules attach themselves to haemoglobin. The body’s cells need oxygen to live and perform their various duties.
The bone marrow needs enough dietary iron and some vitamins to manufacture haemoglobin. If you do not consume enough iron in your diet, the red blood cells will not be able to carry oxygen around the body effectively.
Causes of anaemia
Anaemia can have many causes, including:
- Dietary deficiency – lack of iron, vitamin B12 or folic acid in the diet.
- Malabsorption – where the body is not able to use the nutrients in the diet, caused by conditions such as coeliac disease.
- Inherited disorders – such as thalassaemia or sickle cell disease.
- Autoimmune disorders – such as autoimmune haemolytic anaemia, where the immune cells attack the red blood cells and decrease their life span.
- Chronic diseases – such as rheumatoid arthritis and tuberculosis.
- Hormone disorders – such as hypothyroidism.
- Bone marrow disorders – such as cancer or infection.
- Blood loss – due to trauma, surgery, cancer, peptic ulcer, heavy menstruation, bowel cancer or frequent blood donations.
- Drugs and medications – including alcohol, antibiotics, anti-inflammatory drugs or anti-coagulant medications.
- Infection – such as malaria and septicaemia, which reduce the life span of red blood cells.
- Periods of rapid growth or high energy requirements – such as puberty or pregnancy.
Symptoms of anaemia
Depending on the severity, the symptoms of anaemia may include:
- Pale skin
- Tiring easily
- Drop in blood pressure when standing from a sitting or lying position (orthostatic hypotension) – this may happen after acute blood loss, like a heavy period
- Frequent headaches
- Racing heart or palpitations
- Becoming irritated easily
- Concentration difficulties
- Cracked or reddened tongue
- Loss of appetite
- Strange food cravings.
Groups at high risk
Certain people are at increased risk of anaemia, including:
- Menstruating women
- Pregnant and breastfeeding women
- Babies, especially if premature
- Children going through puberty
- People with cancer, stomach ulcers and some chronic diseases
- People on fad or crash diets
Diagnosis of anaemia
Depending on the cause, anaemia is diagnosed using a number of tests including:
- Medical history – including any chronic illnesses and regular medications
- Physical examination
- Blood tests – including complete blood count and blood iron levels, vitamin B12, folate and kidney function tests
- Urine tests – for detecting blood in the urine
- Gastroscopy or colonoscopy
- Bone marrow biopsy
- Faecal occult blood test – examining a stool sample for the presence of blood.
Treatment for anaemia
Treatment depends on the cause and severity, but may include:
- Vitamin and mineral supplements – in the case of deficiency.
- Iron injections – if the person is very low on iron.
- Vitamin B12 (by injection) – required for pernicious anaemia.
- Antibiotics – if infection is the cause.
- Altering the dose or regimen of regular medications – such as anti-inflammatory drugs, if necessary.
- Blood transfusions – if required.
- Oxygen therapy – if required.
- Surgery to prevent abnormal bleeding – such as heavy menstruation.
- Surgery to remove the spleen (spleenectomy) – in cases of severe haemolytic anaemia.
Take iron supplements only when advised by your doctor. The human body isn’t very good at excreting iron and you could poison yourself if you take more than the recommended dose.
Prevention of anaemia
Some forms of anaemia can’t be prevented because they are caused by a breakdown in the cell-making process. Anaemia caused by dietary deficiency can be prevented by making sure that certain food groups are consumed on a regular basis, including dairy foods, lean meats, nuts and legumes, fresh fruits and vegetables. Vegetarians who prefer not to eat any dairy foods (vegans) should consider taking vitamin and mineral supplements regularly.
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